As a result, the fatty substance can build up in your arteries without a warning
GSD = geometric standard deviation
The drugs stay in your body longer: Both uppers and downers disrupt the digestive tract (an oft-forgotten part of the central nervous system) which can result in a slowed metabolism, and thus, slower processing of drugs in the body
Nicotine influences mood by stimulating brain receptors to release "feel-good" hormones such as dopamine, serotonin, and gamma-aminobutyric acid (GABA) each time you smoke
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